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Dr. Constantinos Tsiamis, Assistant Professor of History of Public Health and of Health of Migrant Populations, Dpt of Public Health and Healthcare, University of Thessaly is being interviewed by Apostolos Verikios, second-year medical student, School of Medicine, Aristotle University of Thessaloniki. This first part of the interview focuses on the three milestones of infectious diseases in history, 1) the Bronze Age, when the first exchange of pathogens between populations begun, 2) Classical Antiquity, with greater exchange of pathogens and with the introduction of zoonoses, 3) 16th century, with the great explorations.