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Asterios Aidonis, Anthropologist, PhD candidate on Biological Anthropology, Department of History and Ethnology, Democritus University of Thrace is being interviewed by Apostolos Verikios, a second-year medical student of the School of Medicine, Aristotle University of Thessaloniki. This fifth part of the interview focusses on the possible effectiveness of trephinations. Taking into account that since the 5th century BC, trephinations were mainly performed to treat cranial fractures, the survival range, from the data available, ranged over 50%, based on the bone reaction existent in the skeletons found in excavations.