This project (2018-1-ES01-KA203-050606) has been funded with support from the European Commission.
This web site reflects the views only of the author, and the Commission cannot be held responsible for any use which may be made of the information contained therein.

This project has been funded with support from the European Commission.
This web site reflects the views only of the author, and the Commission cannot be held responsible for any use which may be made of the information contained therein.

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Glass syringes


Place where the object is located
The Museum of History of Pharmacy, University of Medicine and Pharmacy „Gr. T. Popa”, Iași
Story of the object
Boxes of glass syringes used in the 20th century.

Syringes were invented long before hypodermic needles. Their origins are found in Greek and Roman literature where there are descriptions of hollow reeds for the ritual of anointing the body with oil, and as musical instruments using a plunger to alter the pitch. Simple piston syringes for delivering ointments and creams for medical use were described by Galen (129-200 CE) and an Egyptian, Ammar bin Ali al-Mawsili, reported using glass tubes to apply suction for cataract extraction from about 900 CE. In 1650, Pascal’s experimental work in hydraulics stimulated him to invent the first modern syringe which allowed the infusion of medicines. Christopher Wren (better known as an architect than for his medical training), used a ‘cut-down’ technique to intravenously inject dogs with poppy sap through goose quill canulae. By 1660 Drs Major and Esholttz used this method on humans with similar fatal results due to ignorance of suitable dosage and the need for sterilising utensils and the infusion. The disastrous consequences of these experiments delayed the use of injections for 200 years.

The first hypodermic needle was probably made by Francis Rynd in Dublin in 1844, using the technology of annealing the edges of a folded flat strip of steel to make a tube. This was then drawn through increasingly narrower dies whilst maintaining the patency of the needle. The bevelled point is cut and ground, and then the hub is added with its variety of fittings and locks. A syringe has three elements, the barrel (glass, plastic or metal), the plunger and the piston which may be of rubber, mineral, metal or synthetic material but in early examples waxed linen tape or asbestos was wound on a reel to obtain a watertight seal. Charles Pravaz, in France, administered coagulant to sheep in 1853, but it seems that Alexander Wood in Edinburgh combined a functional syringe with a hypodermic needle in the same year, to inject morphine into humans and probably should be credited with inventing the technique. The basic design has remained unchanged though interchangeable parts and the use of plastic resulted in the almost universal use of disposable syringes and needles since the mid-1950s.

Looking to the future of the parenteral administration of medicines and vaccines, it’s likely that there will be increasing use of direct percutaneous absorption, especially for children. Micro-silicon-based needles, so small that they don’t trigger pain nerves are being developed, however, these systems cannot deliver intravenous or bolus injections so hypodermic needles, with or without syringes, are likely to be with us for a long time. They are also required for catheter-introduced surgical procedures in deep anatomical locations.

Source: https://medicine.uq.edu.au/blog/2018/12/history-syringes-and-needles
Unit of the Educational Material connected (5 - 1)
Label
Location : The Museum of History of Pharmacy, University of Medicine and Pharmacy „Gr. T. Popa”, Iași
Period : 20th century